Virtual Reality Rhythm Game

Virtual reality headsets such as the HTC Vive and Oculus Rift bring robust virtual reality technology in the hands of consumers. However, virtual reality technology is still a very new and unexplored domain with a dearth of compelling software that takes advantage of what virtual reality has to offer. Current rhythm games on the virtual reality platform lack a sense of immersion for the player. These games also require players to remain stationary during gameplay. Our solution is a game where players have to hit musical notes that appear in a trail around them. The trail will move in different directions and players have to move and turn around accordingly in order to hit every note and pass a song

An Extended UTAUT Model for the Study of Negative User Adoption Behaviours of Mobile Commerce

An extended Unified Theory of Acceptance and Use of Technology (UTAUT) for mobile commerce (m-commerce) was empirically tested using data collected from a web survey distributed to and through the Hong Kong undergraduates and postgraduates. The partial least squares (PLS) technique of the structural equation modeling (SEM) was used to evaluate the causal model and the confirmatory factor analysis (CFA) was performed to examine the reliability and validity of the measurement model. Findings indicated that the new construct of Disturbance Concerns (DC) is a significant factor affecting users’ behavioural intention. This study aims to understand both the positive and negative factors that can significantly explain user acceptance intention and use behaviour so that service providers can adjust their strategies for providing successful m-commerce services. It also provides a base for further research on the user acceptance models of new information systems

West Nile Virus and Pattern Recognition Receptors

West Nile Virus (WNV), RNA virus is a member of the flaviviridae family that causes flu like symptoms in infected individuals, however in 1-2% cases, it causes severe neurological diseases such as encephalitis. There is no antiviral or vaccine approved so far to prevent WNV disease, therefore research to understand immune pathology is very important. Pattern Recognition Receptors (PRR) are proteins that are expressed by cells to detect virus infection and play an important role in the innate immune system. When a PRR such as Toll-Like Receptors (TLR) and Nod-Like Receptors (NLR) detects a replicating virus, signals are sent out to warn the body and other neighboring cells that there is a foreign presence within the body. These signals include production of antiviral cytokines and interferons (IFN) that recruit the leukocytes to help fight off the infection. However, it has been discovered that different viruses produce unique cell signals that may act as either a positive and/or negative regulator of the cytokine production and the effectiveness of the immune system. My lab works on understanding the function of two novel innate immune molecules, NLRC5 (a member of NLR family) and TREM-1 (amplifier of inflammation). Therefore, this project will involve WNV infection of mouse immune cells from wild-type mouse and mouse deficient with NLRC5 and TREM-1 and compare specific innate immune markers using real-time RT-PCRs. At the end of my training, I will gain understanding of the research conducted in infectious disease area and will also learn several important techniques

A Meta-Analysis of Procedures to Change Implicit Measures

Using a novel technique known as network meta-analysis, we synthesized evidence from 492 studies (87,418 participants) to investigate the effectiveness of procedures in changing implicit measures, which we define as response biases on implicit tasks. We also evaluated these procedures’ effects on explicit and behavioral measures. We found that implicit measures can be changed, but effects are often relatively weak (|ds| \u3c .30). Most studies focused on producing short-term changes with brief, single-session manipulations. Procedures that associate sets of concepts, invoke goals or motivations, or tax mental resources changed implicit measures the most, whereas procedures that induced threat, affirmation, or specific moods/emotions changed implicit measures the least. Bias tests suggested that implicit effects could be inflated relative to their true population values. Procedures changed explicit measures less consistently and to a smaller degree than implicit measures and generally produced trivial changes in behavior. Finally, changes in implicit measures did not mediate changes in explicit measures or behavior. Our findings suggest that changes in implicit measures are possible, but those changes do not necessarily translate into changes in explicit measures or behavior

Acanthosis Nigricans in a Patient with Urothelial Carcinoma Treated with PD-L1 Inhibitor Avelumab, and Secondary Adrenal Insufficiency

Acanthosis nigricans (AN) describes hyperkeratotic and hyperpigmented skin changes and its pathophysiology is linked to the activation of epidermal growth factor receptors. Current literature shows that AN is most commonly diagnosed at the time of the underlying pathology, which may occur under benign or malignant conditions. This case presentation demonstrates the occurrence of AN in a patient following the diagnosis of urothelial carcinoma and ongoing treatment with PD-L1 inhibitor immunotherapy. Subsequent investigations ruled out a secondary malignancy or disease progression; however, metabolic screening identified secondary glucocorticoid induced adrenal insufficiency. AN was persistent in this patient despite adequate treatment, which highlights its co-occurrence in both benign and paraneoplastic conditions

A Screening tool for Identification of Victims of Commercial Sexual Exploitation of Children

Background: Commercial sexual exploitation of children (CSEC) and sex trafficking have only recently been recognized as problems by healthcare providers. Both UNICEF (2014) and the Institute of Medicine (2013) have stressed the need for systematic research to assist healthcare providers in the identification of victims. The aim of this poster is to describe initial findings relating to the development of a screening tool to identify CSEC victims. Methods: Twenty-seven sites nationwide (e.g., emergency departments and specialized clinics) participated in a study to validate a screening tool for identifying CSEC victims in an outpatient setting. The study was conducted under approval from the Institutional Review Board at Children’s Healthcare of Atlanta. Inclusion criteria for the study generally involved being an English-speaking adolescent aged 11-18 years. Results: Study enrollment is ongoing. Preliminary data for 210 youth were analyzed for this abstract. The sample was diverse with respect to age (M=14.59 years, SD=1.490 years) and ethnicity (56.4% Caucasian, 31.8% African American, 3.9% mixed race, and 7.8% Hispanic); the sample was predominantly female (92.8%). Of the 210 youth in the sample, 115(54.8%) have had sex. Of these 115 youth, 13(11.3%) have traded sex for money, drugs, or housing; 7(58.3%) of 12(10.4%) complied when asked by someone to have sex with another person; 8(61.5%) of 13(11.3%) performed sexual acts in public when propositioned; and 19(45.2%) of 42(36.5%) shared provocative photos when prompted. Medical providers flagged 14 youth (6.7% of total 210) as potential CSEC victims. Conclusions: The screening tool shows promise for effective identification of CSEC victims. This poster will present additional data and further quantitative analyses exploring the influences of sexual behavior, drug and alcohol use, and other factors on the risk of becoming a CSEC victim. Implications for researchers and clinicians will also be discussed

Views of young people with chronic conditions on transition from pediatric to adult health services

PURPOSE: This study sought to identify and describe the views of young people with chronic conditions about the transition from pediatric to adult services. METHODS: Q methodology was used to identify young people’s views on transition. A set of 39 statements about transition was developed from an existing literature review and refined in consultation with local groups of young people. Statements were printed onto cards and a purposive sample of 44 young people with chronic health conditions was recruited, 41 remaining in the study. The young people were asked to sort the statement cards onto a Q-sort grid, according to their opinions from “strongly disagree” to “strongly agree.” Factor analysis was used to identify shared points of view (patterns of similarity between individual’s Q-sorts). RESULTS: Four distinct views on transition were identified from young people: (1) “a laid-back view of transition;” (2) “anxiety about transition;” (3) “wanting independence and autonomy during transition;” and (4) “valuing social interaction with family, peers, and professionals to assist transition.” CONCLUSIONS: Successful transition is likely to be influenced by how young people view the process. Discussing and understanding young people’s views and preferences about transition should help clinicians and young people develop personalized planning for transition as a whole, and more specifically the point of transfer, leading to effective and efficient engagement with adult care

Critical Aspects of the Inclusive Environmental for the Well-being of Building Occupant – A Review

In the property, design and construction industry the main focus of sustainability has been seen to affect the environmental such as climate change and resource depletion. Even though building may meet the recommended standards overall, but yet occupants still complain about several aspects. Indoor environmental quality consequently affects health, productivity and well-being of building occupants as most of them spend their time in indoor space. Therefore they are at risks for air pollutant occurs in the indoor air of dwellings such as volatile organic compounds, paints, ventilation, and others environmental pollutant. This paper reviews the potential health consequences in changes of climates change whereby developed countries contributed in energy consumption and greenhouse gas emissions. From the review search by 57 publications, the literature discussing about how thermal, acoustic and visual comfort as well as indoor air quality affects the satisfaction in indoor environmental quality and impacts to the human health. However, from the undertaken review most of the studies only highlighted on one aspects of indoor environmental quality. A number of critical aspects which give direct impacts to occupants have been identified. Subsequently, among all aspects such as lighting, ventilation, acoustics or humidity and thermal but thermal comfort perceived to influence overall satisfaction of occupants in the building. Thus, from the study revealed the critical aspects of indoor environment and contribute to the improvement for well-being and productivity of building occupants